Synthesis of Compound B
Andrew Stone/Peter Somers/Vana Hendrycks
We began with 1,1-dibromopropane and reacted it with 2 equivalents of acetylide ions (p.262) which will replace the Br groups through a SN2 substitution reaction. This results in two triple bonds, which we then remove with addition of hydrogen in platinum catalyst, giving us our desired product. Stereochemistry is unimportant in this product because it has no chirality centers.