-
First react with Magnesium in Tetrahydrafurian (THF), and then use a ketone
to add three carbons to the chain..
-
The hydroxyl group was replaced by bromine using PBr3
-
Then Na makes an alkyne anion, and adds an alkyl bromide.
-
Lithium in ammonia forms the trans product.
-
PBr3 replaces the hydroxyl group.
-
Mg in THF and then water replaces bromine with hydrogen.
|