Trained as a historian of Christianity, Professor Lagerquist has long been interested in the interaction of religion and culture. Her graduate work focused on Christianity in the USA, with particular attention to Norwegian-American Lutheran women, including those enrolled at St. Olaf during its early decades.  In The Lutherans she traces the larger history of Lutherans in the USA. She has taken students to Greece and Turkey for an interim course exploring sacred place and to India to study religions of India. After leading Global Semester in 2007-08 she developed a BTS-T course on Christianity in India. In addition she offers Lutheran Heritage and Reading the Bible Around the World (Religion 121). She also teaches in the American Conversations program which she helped to develop.

DeAne began her academic career as a student at California Lutheran College followed by masters study at Luther Seminary and doctoral study at the University of Chicago Divinity School.